Arylnaphthalide Lignans from Cleistanthus collinus
نویسندگان
چکیده
منابع مشابه
Cleistanthus collinus poisoning.
Cleistanthus collinus is an extremely toxic plant poison. Cleistanthin A and B, the toxins of Cleistanthus collinus, are diphyllin glycosides which produce cardiac arrhythmias, urinary potassium wasting, hypoxia, metabolic acidosis and hypotension. We report ARDS, distal renal tubular acidosis and distributive shock secondary to inappropriate vasodilatation in a case following ingestion of its ...
متن کاملA clinical and laboratory profile of Cleistanthus collinus poisoning.
AIMS 1. To study the clinical features in patients with Cleistanthus collinus poisoning, 2. To study in them the effect of Cleistanthus collinus poisoning on the various organ systems and metabolic parameters using standard laboratory investigations. METHODS All patients admitted to the hospital between September 1998 and April 2000 were studied. Statistical analysis of the results was done u...
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The isolation and characterization of two new arylnaphthalide lignans, jusmicranthin 1 and justirumalin 5, in addition to helioxanthin 4, taiwanin C 8, retrohelioxanthin 9 and justicidin A 10 from J. neesii, have been reported. Structure of 1 has been deduced as its ethyl and methyl ethers. Compound 1 is the first member .of angularly fused arylnaphthalide lignans having hydroxyl/alkoxyl group ...
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Eight new aryltetralin lignans, cleisindosides A-F (1-6), picroburseranin (7), and 7-hydroxypicropolygamain (8), were isolated from the fruits of Cleistanthus indochinensis (Euphorbiaceae). The structures of the isolates were established on the basis of their one- and two-dimensional NMR spectral data, as well as their mass spectrometric data. Compound 7 was found to have potent cytotoxicity ag...
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The study was conducted to determine the effects of boiled extract of Cleistanthus collinus on rats by observing ECG changes and electrolyte levels in serum and urine. Influence of minoxidil and glibenclamide on Cleistanthus collinus induced toxicity was determined. ED50 for arrhythmia, changes in contractility and heart rate were recorded using the isolated frog heart. Cleistanthus at low dose...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2003
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.51.1299